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• Human platelet lysate is an alternative to FBS in culture. It is obtained from the liquid fraction of uncoagulated blood or blood plasma, which is rich in platelets and contains lipids, clotting factors but above all hormones + proteins such as albumin = hPL can be produced from a simple blood donation.
• Culture supplement, not full replacement:
Benefits:
• XENO-FREE în order to work without animal compounds à Contains only human compounds (contains fewer microorganisms / mycoplasma / endotoxins)
• Promotes in vitro growth of mesenchymal stem cells with 5% hPL à Contains many growth factors as naturally present in BSF. With the serum we use a DMEM high w/glucose medium and 10% FBS
• Low variation between batches
• Reduces cell senescence (degradation of cell functions that cause aging of organisms) after a long period of testing
• Used primarily for the growth of MSCs and other human cells