System for 3D cell culture thanks to the transient magnetization of cells that naturally attach to the NanoShuttle-PL magnetic beads.
Thanks to the magnetic force, the cells are ready for either magnetic levitation or spheroid printing, to form 3D in vitro representation models.
• in vitro reproduction of the native tissue environment
• Versatile system compatible with all cell types even in co-culture
• 3D model formation in a few hours after incubation with magnetic beads
• Allows cell co-culture
• No impact of the magnetized beads on the cells (proliferation, viability, phenotype ...)
• Centered positioning of the spheroids
• No specialized equipment, no media, no artificial substrate
• Easy to handle, no sample loss
Specificities
:
• Nano-particles assembly (50 nm diameter), does not bind any specific receptors, works with all cell types - attaches to the plasma membrane electrostatically
• Consists of biocompatible gold, iron oxide and Poly-L-Lysine
• No effects on proliferation, viability, metablism, oxydative stress, phenotype
• Does not disturb experimental techniques such as immunohistological labelling, fluorescence detection, HR microscopy, Western Blot, PCR/qPCR ...