System for 3D cell culture thanks to the transient magnetization of cells that naturally attach to the NanoShuttle-PL magnetic beads.
Thanks to the magnetic force, the cells are ready for either magnetic levitation or spheroid printing, to form 3D in vitro representation models.
• in vitro reproduction of the native tissue environment
• Versatile system compatible with all cell types even in co-culture
• 3D model formation in a few hours after incubation with magnetic beads
• Allows cell co-culture
• No impact of the magnetized beads on the cells (proliferation, viability, phenotype ...)
• Centered positioning of the spheroids
• No specialized equipment, no media, no artificial substrate
• Easy to handle, no sample loss
Specificities
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Transiently and non-invasively magnetized cells are placed in a Cell-Repellent plate. A magnet placed above the plate attracts the cells to the air/medium interface. Magnetic forces bundle the cells together, favouring intercellular interactions at the origin of the extracellular matrix synthesis.